The volume explores the history of the settlement of Civitavecchia (Centumcellae) starting from its origins, passing through the important logistical role assumed in the imperial age, up to its evolutions in the Middle Ages. The research takes up important international studies previously carried out which have decreed the strong archaeological relevance of this city of southern Etruria. The first chapter deals with the main reconnaissance and excavation projects that have been interested in the reconstruction of the late ancient and medieval landscapes in southern Etruria. The second part (chapters II-V) focuses on the hinterland of Civitavecchia and on all the elements that conditioned the structure of this territory from the second century AD, the time of the foundation of Centumcellae, to the fifteenth century. The area lacks archaeological data from the late Middle Ages, but the wealth of documentary sources has nevertheless allowed us to follow the events that accompanied the formation of the castral settlements.